Publications

View and download slide summaries of the latest original articles focusing on therapies in immune-mediated inflammatory diseases including rheumatology, dermatology, and gastroenterology. All materials produced by the team are subsequently reviewed and approved by individual Steering Committee members.

November 2025

Association of BMI, BMR, BSA, and body weight with psoriasis severity and treatment response: Evidence from a real-world cohort

J Transl Med 2025;23:1129 Doi: 10.1186/s12967-025-07130-w

Xu Y,

Peng C,

Tang S,

Zhang Y,

Zhen Y,

Yin Y,

Wang X,

Ding Y,

Yu Q,

Ma R,

Shi Y

Xu et al. showed that elevated BMI, BSA, body weight, and basal metabolic rate are associated with more severe PsO and diminished treatment efficacy, especially for those treated with biologics. Authors investigated the associations of BMI, basal metabolic rate, BSA, and body weight with baseline PsO severity and therapeutic response across different treatment modalities.

Keywords:

Skeletal muscle effects of Janus kinase inhibition in rheumatoid arthritis (RAMUS): a single-arm, experimental medicine study

Rheumatology 2025 Epub ahead of print doi: 10.1016/S2665-9913(25)00184-5

Bennett et al, showed that tofacitinib treatment in adults with rheumatoid arthritis led to a significant increase in lower limb and thigh muscle volume, accompanied by rises in serum creatinine without evidence of renal impairment.