Impacto dos AINEs na incidência cumulativa de 8 anos de eventos cardiovasculares graves em pacientes com espondilite anquilosante: Um estudo em nível nacional

Rheumatology (Oxford). 2023 doi: 10.1093/rheumatology/kead072

MACEs were observed in patients newly receiving compensation from the Long-term Illness Scheme for AS. The objective of this study was to describe the incidence of MACEs in French patients newly benefiting from the French LTI for AS. The study also sought to evaluate the effect of various treatments on the risk of MACE occurrence.

These data also suggest that in active axSpA NSAIDs and anti-TNFs may have an overall cardiovascular protective effect, unlike anti-IL17. Overall, the results of this publication are reassuring about the use of long-term NSAIDs in SpA.