Opportunistic Infections Associated with Janus Kinase Inhibitor Treatment for Rheumatoid Arthritis: A Structured Literature Review

Structured literature review shows a varied incidence of opportunistic infections (OIs) among RA patients exposed to JAK inhibitors.

The availability of JAK inhibitors has transformed the management of RA, however, the emergence of OIs associated with their use is highly relevant to their safe use in clinical practice.

To this end, Winthrop, et al. conducted a structured literature review to summarise reports of OIs associated with JAKinib treatment for RA in clinical trials.