Infecções Oportunistas Associadas com o Tratamento com Inibidores de Janus Quinase em Artrite Reumatoide: Uma Revisão Estruturada da Literatura

Structured literature review shows a varied incidence of opportunistic infections (OIs) among RA patients exposed to JAK inhibitors.

The availability of JAK inhibitors has transformed the management of RA, however, the emergence of OIs associated with their use is highly relevant to their safe use in clinical practice.

To this end, Winthrop, et al. conducted a structured literature review to summarise reports of OIs associated with JAKinib treatment for RA in clinical trials.