About
This forum is an educational website developed under the auspices of the University of Glasgow and is dedicated to the dissemination of the latest developments in cytokine signalling. It provides continuing medical education to clinicians around the globe to facilitate greater understanding of the science of cytokines and cytokine signalling, and its implications for clinical practice.
The programmes are free from commercial bias, and feature leading experts sharing their knowledge and experience in the form of video tutorials.
Publications
Benefit–risk analysis of upadacitinib versus adalimumab in patients with rheumatoid arthritis and higher or lower risk of cardiovascular disease
Publications
Anti-TL1A antibody, afimkibart, in moderately-to-severely active ulcerative colitis (TUSCANY-2): A multicentre, double-blind, treat-through, multi-dose, randomised, placebo-controlled, Phase 2b trial
Publications
Ixekizumab and malignant neoplasms A pooled analysis of data from 25 randomized clinical trials
Podcasts
Difficult-to-treat disease in Rheumatology Podcast Professors Iain McInnes and Peter Nash
Publications
Efficacy and safety of upadacitinib for patients with immune-mediated inflammatory diseases: a systematic review and meta-analysis
Podcasts
Discussing axSpA: Secukinumab treatment outcomes on sustained remission and skeletal health in axSpA
Podcasts
Discussing RA: Impact of TOF on BMI, UPA monotherapy in MTX-IRs, and JAKis vs TNFis treatment
Publications
Comparative risk of incident malignancies in rheumatoid arthritis patients treated with janus kinase inhibitors or bDMARDs: observational data from the German RABBIT register
Publications
Clinical trial: Association between early disease clearance and long-term outcomes—4-year results from the Phase 3 UNIFI study of ustekinumab in ulcerative colitis
Publications
Dual JAK and ROCK inhibition with CPL’116 in patients with rheumatoid arthritis with inadequate response to methotrexate: a randomised, double-blind, placebo controlled, phase 2 trial
Publications
Effects of secukinumab on skeletal microarchitecture and vertebral fractures in patients with axial spondyloarthritis using HR‑pQCT
Publications
Risk of new-onset inflammatory bowel disease in psoriasis patients treated with five different interleukin inhibitors: a systematic review and meta-analysis
Podcasts
Podcast: AuToDeCRA, June 2025
Publications
Long-term efficacy and safety of upadacitinib in patients with moderately to severely active ulcerative colitis: an interim analysis of the phase 3 U-ACTIVATE long-term extension study
Publications
Analysis of the impact of tofacitinib treatment on weight and body mass index in patients with rheumatoid arthritis
Publications
Upadacitinib as monotherapy in patients with rheumatoid arthritis and prior inadequate response to methotrexate: results at 260 weeks from the SELECT-MONOTHERAPY randomised study
Publications
Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles
Publications
Risk of major adverse cardiovascular events and venous thromboembolic events between patients with psoriasis or psoriatic arthritis on tumor necrosis factor inhibitors, interleukin 17 inhibitors, interleukin 12/23 inhibitors, and interleukin 23 inhibitors: An emulated target trial analysis
Publications
Appendicectomy plus standard medical therapy versus standard medical therapy alone for maintenance of remission in ulcerative colitis (ACCURE): a pragmatic, open-label, international, randomised trial
Podcasts
Discussing PsA: Real-world data on biologic switching and the development of EMMs
Publications
Four-year secukinumab treatment outcomes in European real-world patients with axial spondyloarthritis and psoriatic arthritis
Publications
Cardiovascular disease risk in patients with psoriasis receiving biologics targeting TNF-α, IL-12/23, IL-17, and IL-23: A population-based retrospective cohort study
Podcasts
Discussing RA: MACE in RA, data from the "JAK-pot" study, and combination therapy in MTX-IR RA
Publications
Deucravacitinib in patients with plaque psoriasis who screened positive for psoriatic arthritis: improvements in joint pain and the impact of musculoskeletal symptoms
Podcasts
Webinar Highlights Podcast: Advancing Patient Care Through an Interdisciplinary Approach to IMIDs
Podcasts
Author Interview: Dr Saqr Alsakarneh, May 2025
Publications
Prevalence and predictors of achieving sustained remission in psoriatic arthritis. A Swedish nationwide registry study
Publications
Obefazimod in patients with moderate-to-severely active ulcerative colitis: efficacy and safety analysis from the 96-week open-label maintenance phase 2b study
Publications
Biologic switching in psoriatic arthritis: Insights from real-world data and key risk factors
Podcasts
Discussing RA: MACE, VTE, and malignancy in filgotinib RA and UC patients, and MACE related to JAKis
Podcasts
Discussing axSpA: JAKi cycling and long-term safety of bimekizumab in patients with axSpA or PsA
Publications