Cardiovascular disease risk in patients with psoriasis receiving biologics targeting TNF-α, IL-12/23, IL-17, and IL-23: A population-based retrospective cohort study
PLoS Med 22(4): e1004591 DOI: org/10.1371/journal.pmed.1004591
Lin et al. compared the risk of CVD in patients with psoriasis who were prescribed biologics or oral therapies and assessed the association between different classes of biologics and CVD risk. Patients with psoriasis-prescribed biologics exhibited a reduced risk of incident CVDs compared with those receiving oral antipsoriatic drugs.
The observed lower risk with biologics was seen across different heart conditions, including stroke, arrhythmias, inflammatory heart diseases, ischemic heart diseases, heart failure, non-ischemic cardiomyopathy, thrombotic disorders, peripheral arterial occlusive diseases, and MACE.
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