Dados de eficácia e segurança baseados em condições pré-existentes ou históricas na linha de base para pacientes com artrite reumatóide ativa que foram tratados com baricitinibe
Ann Rheum Dis. 2019 Aug;78(8):1135-1138.
In a post-hoc analysis, BARI 4 mg showed similar efficacy and safety during placebo-controlled and LTE observation periods regardless of the presence or absence of select comorbidities in RA patients.Patients with RA have a high prevalence of comorbidities. This post-hoc analysis investigated the effect of select comorbidities (depression, osteoporosis, hepatic, cardiovascular or pulmonary disorders) on the efficacy and safety of BARI 4 mg QD in patients with moderate-to-severe active RA and ina...