Impact of treatments on fatigue in axial spondyloarthritis: a systematic review and meta-analysis
Rheumatology (Oxford). 2024 Oct 10:keae549 doi 10.1093/rheumatology/keae549 Epub ahead of print
Delcourt et al. conducted a systematic review and meta-analysis revealing that both pharmacological (DMARDs) and non-pharmacological interventions reduce fatigue in axSpA patients over short and medium terms, with greater efficacy seen when combined.
The study reviewed 34 studies, assessing fatigue outcomes in axSpA treatments, showing significant improvement from anti-TNF, anti-IL17, and JAK inhibitors in most cases, though no difference in efficacy was observed across DMARD types.
