Diferenças relacionadas ao sexo nas características dos pacientes e na eficácia e segurança de terapias avançadas em ensaios clínicos randomizados em artrite psoriática: Uma revisão sistemática da literatura e meta-análise
Lancet Rheumatol 2023;5:e716–27
In this study, Eder, et al. performed a systematic literature review and meta-analysis of RCTs to assess information on participants’ characteristics and rates of American College of Rheumatology response and minimal disease activity by sex. The authors found that the biological sex of patients with PsA influences their response to advanced therapies, but the effect varies by drug class.
It was acknowledged that selective reporting might have influenced these results, and future trials should report baseline characteristics and endpoint results by sex.
