Différences liées au sexe dans les caractéristiques des patients et dans l'efficacité et la sécurité des thérapies avancées dans les essais cliniques randomisés sur le rhumatisme psoriasique : Une revue systématique de la littérature et une méta-analyse
Lancet Rheumatol 2023;5:e716–27
In this study, Eder, et al. performed a systematic literature review and meta-analysis of RCTs to assess information on participants’ characteristics and rates of American College of Rheumatology response and minimal disease activity by sex. The authors found that the biological sex of patients with PsA influences their response to advanced therapies, but the effect varies by drug class.
It was acknowledged that selective reporting might have influenced these results, and future trials should report baseline characteristics and endpoint results by sex.
