Effet du golimumab en intraveineuse sur la fatigue et relation avec la réponse clinique chez les adultes atteints de spondylarthrite ankylosante active dans l'étude de phase 3 GO-ALIVE
Rheumatol Ther. 2023;10(4):983–999 doi 10.1007/s40744-023-00556-y
Administration of IV-golimumab 2 mg/kg improves fatigue symptoms in axial spondylitis in a 52 Week study. At Week 16 of treatment, improvements in ASAS, ASDAS, BASDAI and SF-36 scores were observed at week 16 of treatment.
This post-hoc analysis of the GO-ALIVE study specifically investigates fatigue symptoms related to AxSpA. Participants were randomised 1:1 to golimumab or a placebo, with the placebo group introduced to golimumab in Week 16. The placebo group had similar improvements to the treatment group at Week 52.
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