関節リウマチ、乾癬性関節炎、強直性脊椎炎を対象とした１５０００人年におよぶウパダシチニブの安全性
RMD Open. 2023;9(1):e002735 doi: 10.1136/rmdopen-2022-002735
Integrated analysis of the safety profile of upadacitinib demonstrates that it was generally well-tolerated in RA, PsA, AS and AD, with no new safety risks identified, compared with previous reports.
Several safety risks have been associated with JAK inhibitor use, and recent data from the ORAL Surveillance study have highlighted the need to further characterise the safety profile of these drugs. To this end, Burmester, et al. evaluated the long-term safety profile for upadacitinib, based on more than 6000 patients and 15 000 patient-years of exposure.
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