JAK阻害薬と他の治療薬における静脈血栓症: 関節リウマチ患者におけるスウェーデンの安全性比較研究

Nationwide register-based study in Sweden finds that patients with RA treated with JAKinibs in routine clinical practice are at increased risk of venous thromboembolism (VTE), compared with those treated with bDMARDs, an increase numerically confined to pulmonary embolism.

Following recent data, and the FDA and EMA warnings, regarding VTE risk with JAKinibs, Molander, et al. aimed to assess and compare the incidence of VTE, by type, in patients with RA treated with JAKinibs or bDMARDs, in clinical practice.