Thromboembolie veineuse avec les inhibiteurs de JAK et d'autres médicaments immunomodulateurs : une étude comparative suédoise de sécurité chez des patients atteints de polyarthrite rhumatoïde
Ann Rheum Dis. 2022. doi: 10.1136/ard-2022-223050
Nationwide register-based study in Sweden finds that patients with RA treated with JAKinibs in routine clinical practice are at increased risk of venous thromboembolism (VTE), compared with those treated with bDMARDs, an increase numerically confined to pulmonary embolism.
Following recent data, and the FDA and EMA warnings, regarding VTE risk with JAKinibs, Molander, et al. aimed to assess and compare the incidence of VTE, by type, in patients with RA treated with JAKinibs or bDMARDs, in clinical practice.
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