Structure of the pseudokinase-kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition
Proc Natl Acad Sci U S A. 2014 May 19. pii: 201401180. [Epub ahead of print]
View and download slide summaries of the latest original articles focusing on therapies in immune-mediated inflammatory diseases including rheumatology, dermatology, and gastroenterology. All materials produced by the team are subsequently reviewed and approved by individual Steering Committee members.
Proc Natl Acad Sci U S A. 2014 May 19. pii: 201401180. [Epub ahead of print]
Nat Struct Mol Biol. 2014 May;21(5):443-8. doi: 10.1038/nsmb.2807. Epub 2014 Apr 6
J Immunol 2014; 192:4417-4424
J Rheumatol 2014;41;837-852
Arthritis Research and Therapy 2014,16:R102
Arthritis Research and Therapy 2014, 16:R99
BMC Medicine 2014, 12:43
Clin Cancer Research doi:10.1158/1078-0432.CCR-13-0279
. ARD published online first 13 Feb 2014. Doi: 10.1136/annrheumdis-2013-204105
Arthritis and Rheumatology March 2014:66;513-522