Updacitinib Melhora os Desfechos Reportados pelos Pacientes em Pacientes com Artrite Reumatoide e Resposta Inadequada a Drogas Antirreumáticas Modificadoras de Doença Sintéticas Clássicas: Resultados de SELECT-NEXT
Arthritis Res Ther . 2019 Dec 9;21(1):272.
In SELECT-NEXT, UPA demonstrated clinically meaningful improvements in patient reported outcomes compared to PBO in patients with RA who had an inadequate response to csDMARDs. In this post hoc analysis, the effect of UPA 15 or 30 mg on patient reported outcomes were assessed and compared to PBO.Eligible patients (661) with an inadequate response to csDMARDs were randomly assigned 2:2:1:1 to receive background csDMARD therapy with either UPA 15 mg, UPA 30 mg or PBO. PROs collected at Wk4 and Wk1...