Dor e inflamação como mediadores do efeito do tratamento com tofacitinibe sobre a fadiga em pacientes com espondilite anquilosante: Uma análise de mediação
Rheumatol Ther 2023;10(4):1073–1087 doi 10.1007/s40744-023-00570-0
Kristensen, et al. used mediation modelling to show that tofacitinib indirectly improved fatigue symptoms via back pain and morning stiffness. This study was carried out using FACIT-F- and BASDAI Q1-based models to determine the relationship between these variables.