Tofacitinib Modula a Resposta Imune in vitro de Células T CD4+ VZV – Específicas em Linfócitos de Pacientes com Artrite Reumatoide
Rheumatology (Oxford) 2019;58(11):2051–60
TOF significantly modulated the Th1 response to Varicella-zoster-virus (VZV). The poor VZV-specific cellular immune responses in patients with RA may be considered in recommendations regarding appropriate vaccination strategies for enhancing the VZV-specific Th1 response.Previous studies have shown that treatment with JAKinibs increases HZ incidence compared with conventional DMARDs. This cross-sectional in vitro study aimed to investigate the effect of TOF on the VZV-specific T cell immune resp...