バリシチニブは関節リウマチにおいてLDL-C と HDL-C 上昇を誘導する: 無作為化対照比較試験のメタ解析
Lipids Health Dis. 2019 Feb 18;18(1):54.
This study confirmed that BARI induced a stable dose-dependent increase in LDL-C and HDL-C levels. There was no significant difference of CV risk between BARI and placebo groups.High risk of CV events is strongly associated with RA. Mechanisms underlying the excess risk of CV events in RA remains unclear. This study aims to provide additional insight into the clinical safety of BARI, focusing on the effects of BARI on LDL-C and HDL-C levels and CV risk. A Cochrane analysis was performed on studi...