体軸型脊椎関節炎に対するビメキズマブの有効性と安全性: 2つのフェーズ3無作為化対照試験結果
Ann Rheum Dis. 2023 Jan 17 doi: 10.1136/ard-2022-223595
Bimekizumab may therefore offer patients with axSpA an effective treatment option with a novel mode of action.
February 2023
January 2023
トファシチニブとメトトレキサート併用で治療され、メトト レキサートを中止した関節リウマチ患者の疾患活動性
Rheumatol Ther. 2022. Epub ahead of print doi: 10.1007/s40744-022-00511-3
This post hoc analysis of data from the ORAL Shift study, concludes that DAS28-4(ESR), CDAI remission and SDAI remission are the metrics most likely to reflect actual disease activity, in the context of tofacitinib in a randomised withdrawal of MTX.
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November 2020
関節リウマチの臨床試験とアメリカのCorrona RAレジストリにおけるTofacitinibと生物学的DMARDsの年齢別 (<65 vs ≥65 歳)の 感染症と重篤感染症発生率
Ann Rheum Dis 2020; DOI: 10.1136/annrheumdis-2020-218992
Reports from clinical trials and the US Corrona RA registry showed that serious infection event (SIE) incidence was higher in older versus younger patients with RA receiving 10 mg BID of TOF and ADA, however, SIE risk was similar between age groups with TOF 5 mg BID and ADA.Data were collected from Phase II–IV tofacitinib studies, and the US Corrona RA registry. The clinical data set evaluated patients receiving TOF 5 and 10 mg BID versus TNFi (ADA/ETN) in RA patients aged ≥50 years. The EMA rec...