Publications

View and download slide summaries of the latest original articles focusing on therapies in immune-mediated inflammatory diseases including rheumatology, dermatology, and gastroenterology. All materials produced by the team are subsequently reviewed and approved by individual Steering Committee members.

December 2022

バリシチニブ治療中の関節リウマチ患者におけるVTE, MACE, 重篤感染症のTNFi治療と比較した評価: レジストリとクレームデータベースを使用した複数データベース試験

Rheumatol Ther. 2022. Epub ahead of print doi: 10.1007/s40744-022-00505-1

Bower H,

Song Y,

Bosan R,

Zhu B,

Mai X,

Deberdt W; B023 Study Consortium

Salinas, et al. evaluate baricitinib safety with respect to VTE, MACE, and serious infection relative to TNFi in patients with RA, in routine care and observe an increased risk of VTE in patients taking baricitinib, compared to TNFi.

Keywords:

February 2019

関節リウマチにおけるバリシチニブの心血管に対する安全性

Arthritis Rheumatol. 2019 Jul;71(7):1042-1055.

Witt S,

Issa M,

Zhang X,

This study indicates no association between exposure to BARI and MACE, arterial thrombotic events (ATE), or congestive heart failure (CHF). Overall IRs for venous thromboembolic event (VTE) in BARI-treated patients falls within the reported range for patients with RA.RA patients have a greater risk of cardiovascular (CV) diseases of arterial ischemic origin, and an increased risk of VTE. Studied frequencies of thromboembolic events in RA populations in the last decade has been reported as 2–3x h...