Phase 2a study assessing the efficacy and safety of tildrakizumab in patients with active AS fails to meet the primary endpoint.

May 2023

体軸関節炎患者にいつセクキヌマブを使うか: 抗TNFα 治療前それとも後?

Reumatol Clin. 19 (2023); 175–179 doi 10.1016/j.reumae.2022.03.007

Secukinumab, an IL-17A monoclonal antibody, was shown to have remarkable efficacy for axSpA in the MEASURE 2 and MEASURE 3 trials. Previous studies have concluded that secukinumab was more efficacious in TNFi-naïve patients.

February 2023

Bimekizumab may therefore offer patients with axSpA an effective treatment option with a novel mode of action.