July 2018

Sarilumab per Artriti Reumatoidi Moderate o Gravi Previamente Trattate: Una Prospettiva del Gruppo di Revisione delle Evidenze su una Valutazione di Singola Tecnologia NICE

Pharmacoeconomics. 2018 Dec;36(12):1427-1437. doi: 10.1007/s40273-018-0677-7

In this National Institute for Health and Care (NICE) single technology appraisal of sarilumab (SAR) monotherapy and combination therapy with methotrexate (MTX), SAR was considered to have similar efficacy to other bDMARDs for treating moderate-to-severe RA with inadequate response to cDMARDs or TNFis. SAR was also considered a cost-effective use of National Health Service (NHS) resources versus some or all of its comparators in most considered populations.NICE is an independent organisation res...

April 2018

Baricitinib per l’Artrite Reumatoide da Moderata a Grave Precedentemente Trattata: Una Prospettiva del Gruppo Evidence Review sui Dati di una Valutazione per Singole Tecnologie del NICE

Pharmacoeconomics 2018 Jul; 36(7):769–78

In this National Institute for Health and Care (NICE) single technology appraisal of baricitinib (BARI) monotherapy and combination therapy with methotrexate (MTX), BARI efficacy was considered comparable to bDMARDs and a cost-effective use of National Health Service (NHS) resources.NICE is an independent organisation responsible for providing national guidance on health technologies in England. To be recommended by NICE, the company must provide evidence to prove BARI’s effectiveness, both clin...

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Tofacitinib per il Trattamento dell’Artrite Reumatoide Dopo il Fallimento di Farmaci Antireumatici Disease-Modifying: Una Prospettiva del Gruppo Revisione delle Evidenze di una Valutazione NICE per Singola Tecnologia

Pharmacoeconomics 2018 Sep; 36(9): 1063–72

In this National Institute for Health and Care (NICE) single technology appraisal of tofacitinib (TOF) plus methotrexate (MTX), TOF had similar efficacy and comparable costs to recommended bDMARDs plus MTX in patients with RA. NICE is an independent organisation responsible for providing national guidance on health technologies in England. To be recommended by NICE, the company must provide evidence to prove TOF’s effectiveness, both clinically and costly. This evidence based review, reports the...

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