Innocuité des DMARD synthétiques et biologiques : une revue systématique de la littérature étayant la mise à jour de 2019 des recommandations EULAR pour la gestion de la polyarthrite rhumatoïde
Annals of the Rheumatic Diseases 2020;79:760-770
This SLR informed the 2019 EULAR taskforce updating recommendations for RA management. Overall, no new safety signals were reported. The known safety profile of bDMARDs was confirmed and extended to tsDMARDS. IL-6i associated lower intestinal perforation has been further confirmed, while VTE and PE concerns in JAKi treatment need further evaluation.Previous updates for the EULAR recommendations on RA pharmacological management were conducted in 2016. In this SLR safety of csDMARDs, tsDMARDs, and...