Étude Comparative d'Innocuité Post-Approbation du Tofacitinib et des Antirhumatismaux Biologiques : Résultats à 5 ans à partir d'un Registre de Polyarthrite Rhumatoïde Basé aux États-Unis
ACR Open Rheumatol. 2021 Feb 11.
Analysis from the US Corrona RA registry has provided the longest-term real-world safety data for a JAK inhibitor to date. The analysis showed that the cohorts had similar adverse events, except for higher herpes zoster rates for tofacitinib initiators vs bDMARDs.Kremer JM, et al. analysed adult patients with RA newly initiating tofacitinib, or a bDMARD, to compare incidence rates of MACE, SIEs, HZ, malignancies and death. VTE data were also collected prospectively and assessed descriptively thr...