Malignité dans les essais cliniques sur l'Upadacitinib pour la polyarthrite rhumatoïde, le rhumatisme psoriasique, la spondylarthrite ankylosante et la spondylarthrite axiale non radiographique
Rheumatol Ther 2023;11(1):97–112 doi 10.1007/s40744-023-00621-6
Rates of malignancy were similar between upadacitinib, adalimumab, and MTX. They were also consistent across RA, PsA, AS and nr-axSpA. A dose-dependent increased rate of NMSC was observed with upadacitinib in RA. For RA and PsA, being older (≥65 years) and male was associated with
an increased risk of malignancy excluding NMSC.