Publications

Haberman et al. analysed prescribing patterns and characteristics of PsA patients with
multi-b/tsDMARD failure, defined as requiring ≥4 b/tsDMARDs. Among 960 patients at the NYU Psoriatic Arthritis Centre, 17% met this criterion. These patients were more likely to be female, obese, and have higher rates of axial involvement and depression. They also exhibited greater disease activity, suggesting that both inflammatory and non-inflammatory factors contribute to multiple treatment failures.

This study examined data from a longitudinal registry to identify risk factors for poor treatment persistence. The findings underscore the importance of precision medicine approaches in PsA, as current therapies often fail to sustain long-term disease control in a subset of patients. The results highlight the need for non-pharmacologic interventions alongside pharmacologic strategies to improve patient outcomes and quality of life.