Long-term clinical outcomes of certolizumab pegol treatment in non-radiographic axial spondyloarthritis stratified by baseline MRI and CRP status
RMD Open 2024;10:e003884 doi: 10.1136/rmdopen-2023-003884 https://pubmed.ncbi.nlm.nih.gov/38724259/
The safety follow-up extension of the C-axSpAnd trial showed that long-term clinical outcomes from certolizumab pegol treatment achieved after 1 year were generally sustained at 3 years across MRI+/CRP+, MRI−/CRP+ and MRI+/CRP− subgroups.
Rudwaleit, et al. randomised patients with nr-axSpA 1:1 to certolizumab pegol 200mg Q2W or placebo in the 52-week double-blind period. At Week 52, the optional safety follow-up extension treated all patients with open-label certolizumab pegol through 156 weeks.
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