Efeito do upadacitinibe na atividade da doença, dor, fadiga, função, qualidade de vida relacionada à saúde e produtividade no trabalho em espondilite anquilosante refratária a biológicos
Rheumatol Ther 2023; 10:679–91 doi 10.1007/s40744-023-00536-2
Upadacitinib significantly improved patient-reported outcomes in AxSpA patients with bDMARD-IR after 14 Weeks of treatment. There were notable improvements in disease activity, pain, fatigue, function, HRQoL, and work productivity.
Navarro-Compán, et al. report results from SELECT-AXIS 2, a phase 3, randomised, double-blind, parallel-group, placebo-controlled trial. This study shows that upadacitinib is a suitable oral drug for bDMARD-IR AxSpA patients.
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