非薬物療法および非生物学的療法の有効性と安全性: 体軸型脊椎関節炎に対する2022 ASAS/EULAR 推奨へのシステマティックレビュー
Ann Rheum Dis 2022; online ahead of print doi:10.1136/ard-2022-223297
Non-pharmacological interventions are important for any rheumatic disease, but especially axSpA, where they represent the cornerstone of treatment. The aim of this study was to produce a systematic literature review on efficacy and safety of non-pharmacological and non-biological pharmacological treatments was performed.
In addition, NSAIDs were also confirmed to be efficacious in axSpA. Alendronate is not effective in axSpA, while limited efficacy of short-term use of high-dose glucocorticoids has been shown. Among tsDMARDs, filgotinib, tofacitinib, and upadacitinib have shown efficacy in radiographic axSpA, with an acceptable short-term safety profile.
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