L'activité initiale de la maladie permet de prédire l'atteinte des objectifs thérapeutiques cDAPSA avec Apremilast : Résultats de phase III chez des patients atteints de rhumatisme psoriasique et DMARD-naïfs
J Rheumatol. 2022 doi: 10.3899/jrheum.210906
Baseline disease activity, as measured by cDAPSA, predicts the achievement of treatment targets in DMARD-naïve patients post- apremilast treatment. To come to this conclusion Mease, et al. analysed data from the PALACE 4 clinical trial which investigated apremilast in DMARD-naïve patients. 175 patients receiving 30mg apremilast from baseline with cDAPSA data available, were analysed.
Overall, this study supports apremilast as an effective treatment for DMARD-naïve patients with PsA regardless of the presence of extraarticular manifestations of the disease.
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