Appendicectomy plus standard medical therapy versus standard medical therapy alone for maintenance of remission in ulcerative colitis (ACCURE): a pragmatic, open-label, international, randomised trial
Lancet Gastroenterol Hepatol. 2025; 10: 550–61 DOI: 10.1016/S2468-1253(25)00026-3
The ACCURE Study Group aimed to evaluate the clinical effectiveness of laparoscopic appendicectomy in maintaining remission in patients with UC. Authors showed that appendicectomy is a viable and safe strategy for reducing the relapse rate in patients with UC compared with standard medical therapy at 1 year, offering a potential addition to standard medical therapies.